The SERPINB3 + SERPINB4 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to SERPINB3. This antibody recognizes Human antigen. The SERPINB3 + SERPINB4 Polyclonal Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells